RU 486 is the first steroidal antiprogesterone in clinical use. It acts by binding to progesterone receptor, thus blocking the effects of progesterone at the uterine level, and provoking endometrial necrosis and shedding.
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... progesterone. RU 486 (10 nmol-10 mumol/l) attenuated the production of all three placental hormones, in a dose-related manner, and its effects on hCG and ...
Aug 23, 2022 · ... progesterone RU 486. Baulieu EE. Eur J Obstet Gynecol Reprod Biol. 1988;28:125–129. [PubMed] [Google Scholar]. 6. Mifepristone ...
However, in the absence of progesterone, RU 486 may form a receptor complex that is active on some promoters [i.e., the potential agonistic effects of RU ...
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Stereochemical complementarity of progesterone, RU 486 and cavities between base pairs in partially unwound double stranded DNA assessed by computer modeling ...
Through its action at the progesterone receptor, mifepristone can cause endometrial thickening and vaginal bleeding, and overall 38% of women enrolled in ...
It binds strongly to the progesterone and glucocorticoid receptor and, to a lesser extent, to the androgen receptor. RU 486 possesses no significant binding ...
an anti-progesterone (RU 486) on ectopic pregnancy. A 28 cases survey. Contraception 1986; 14: 121-123. 45. Nieman LK, Chrousos GP, Spitz I. et a1 ...
early pregnancy, oestrogen receptor, progesterone receptor, RU 486, trophoblast. Issue Section: PREGNANCY · PDF. This content is only available as a PDF. Author ...
Apr 30, 2019 · Hence, we anticipated anti-progesterone (RU 486) supplementation to egg yolk based extender would reduce the incidence of premature ...